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KMID : 0882420180930010050
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Korean Journal of Medicine
2018 Volume.93 No. 1 p.50 ~ p.54
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Hepatic Arterial Infusion Chemotherapy Using the Port System in Advanced Gallbladder Cancer
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Eun Jong-Ryeol
Kim Jae-Woon
Choi Joon-Hyuk
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Abstract
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Gallbladder (GB) cancer is relatively rare and has a poor prognosis, with a median survival time of less than 3 months. It is resistant to chemotherapy. Therefore, the role of systemic chemotherapy is limited. However, administering the anticancer agent directly into the hepatic artery can result in a higher drug concentration in the cancer tissue. In this paper, we report a case of advanced GB cancer treated with hepatic arterial infusion chemotherapy (HAIC) using the port system. The patient received six cycles of HAIC with 5-fluorouracil (750 mg/m2) and cisplatin (25 mg/m2); each cycle lasted for 4 days every month. The tumor showed objective response during HAIC, and the patient survived for 15 months from the first therapy. HAIC using the port system might be a promising therapeutic modality for treating locally advanced GB cancer.
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KEYWORD
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Gallbladder cancer, Chemotherapy, Hepatic artery
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